Polymorphism of Immune Checkpoint Molecules in Hematological Disorders
نویسندگان
چکیده
منابع مشابه
"موارد طحال برداری در بیماریهای خونی"splenectomy in hematological disorders" "
چکیده ندارد.
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Inhibitory molecules such as PD-1, CTLA-4, LAG-3, or TIM-3 play a role to keep a balance in immune function. However, many cancers exploit such molecules to escape immune surveillance. Accumulating data support that their functions are dysregulated in lymphoid neoplasms, including plasma cell myeloma, myelodysplastic syndrome, and acute myeloid leukemia. In lymphoid neoplasms, aberrations in 9p...
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ژورنال
عنوان ژورنال: The Kitakanto Medical Journal
سال: 2019
ISSN: 1343-2826,1881-1191
DOI: 10.2974/kmj.69.67